Liposome Entrapment Parameters 3
نویسندگان
چکیده
Methods for the complete characterizat ion of liposomes prepared by ether-injection are described in detail. The va l id i ty of a t o m i c absorption spectrophotometry Ior measuring markers of trapped volume was checked by comparat ive determinations of markers with established op t i ca l spectrophotometrical methods. The favorable r e su l t s usingl atomic absorption spectrophotometry to quanti tate the marker Mn2+ are of particular relevance as manganese ion is also the paramagnetic probe in n .m.r , m e a s u r e m e n t s of water permeability of liposomes~ our results indicate that in such measurements no other marker need be incorporated.
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